Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms

Leptin (encoded by Lep) controls body weight by regulating food intake and fuel partitioning. Obesity is characterized by leptin resistance and increased endocannabinoid tone. Here we show that leptin infused into the mediobasal hypothalamus (MBH) of rats inhibits white adipose tissue (WAT) lipogene...

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Detalhes bibliográficos
Main Authors: Buettner, Christoph, Muse, Evan D, Cheng, Andrew, Chen, Linghong, Scherer, Thomas, Pocai, Alessandro, Su, Kai, Cheng, Bob, Li, Xiasong, Harvey-White, Judith, Schwartz, Gary J, Kunos, George, Rossetti, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671848/
https://ncbi.nlm.nih.gov/pubmed/18516053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1775
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