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Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

Short-term overfeeding blunts the central effects of fatty acids on food intake and glucose production. This acquired defect in nutrient sensing could contribute to the rapid onset of hyperphagia and insulin resistance in this model. Here we examined whether central inhibition of lipid oxidation is...

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Main Authors: Pocai, Alessandro, Lam, Tony K.T., Obici, Silvana, Gutierrez-Juarez, Roger, Muse, Evan D., Arduini, Arduino, Rossetti, Luciano
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395479/
https://ncbi.nlm.nih.gov/pubmed/16528412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26640
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