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Hypothalamic resistin induces hepatic insulin resistance

Circulating resistin stimulates endogenous glucose production (GP). Here, we report that bi-directional changes in hypothalamic resistin action have dramatic effects on GP and proinflammatory cytokine expression in the liver. The infusion of either resistin or an active cysteine mutant in the third...

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Autori principali: Muse, Evan D., Lam, Tony K.T., Scherer, Philipp E., Rossetti, Luciano
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868785/
https://ncbi.nlm.nih.gov/pubmed/17525801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30440
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