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Adipose-derived resistin and gut-derived resistin-like molecule–β selectively impair insulin action on glucose production

The adipose-derived hormone resistin is postulated to link obesity to insulin resistance and diabetes. Here, the infusion of either resistin or the resistin-like molecule–β (RELMβ) rapidly induced severe hepatic but not peripheral insulin resistance. In the presence of physiologic hyperinsulinemia,...

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Detalhes bibliográficos
Main Authors: Rajala, Michael W., Obici, Silvana, Scherer, Philipp E., Rossetti, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151868/
https://ncbi.nlm.nih.gov/pubmed/12531878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316521
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