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Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

Intraperitoneal injection of purified recombinant Acrp30 lowers glucose levels in mice. To gain insight into the mechanism(s) of this hypoglycemic effect, purified recombinant Acrp30 was infused in conscious mice during a pancreatic euglycemic clamp. In the presence of physiological hyperinsulinemia...

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Detalhes bibliográficos
Main Authors: Combs, Terry P., Berg, Anders H., Obici, Silvana, Scherer, Philipp E., Rossetti, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209474/
https://ncbi.nlm.nih.gov/pubmed/11748271
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