Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation

gACRP30, the globular subunit of adipocyte complement-related protein of 30 kDa (ACRP30), improves insulin sensitivity and increases fatty acid oxidation. The mechanism by which gACRP30 exerts these effects is unknown. Here, we examined if gACRP30 activates AMP-activated protein kinase (AMPK), an en...

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Detalhes bibliográficos
Main Authors: Tomas, Eva, Tsao, Tsu-Shuen, Saha, Asish K., Murrey, Heather E., Zhang, Cheng cheng, Itani, Samar I., Lodish, Harvey F., Ruderman, Neil B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC138607/
https://ncbi.nlm.nih.gov/pubmed/12456889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222657499
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