Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation

gACRP30, the globular subunit of adipocyte complement-related protein of 30 kDa (ACRP30), improves insulin sensitivity and increases fatty acid oxidation. The mechanism by which gACRP30 exerts these effects is unknown. Here, we examined if gACRP30 activates AMP-activated protein kinase (AMPK), an en...

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Bibliografiske detaljer
Main Authors: Tomas, Eva, Tsao, Tsu-Shuen, Saha, Asish K., Murrey, Heather E., Zhang, Cheng cheng, Itani, Samar I., Lodish, Harvey F., Ruderman, Neil B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC138607/
https://ncbi.nlm.nih.gov/pubmed/12456889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222657499
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