Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation

gACRP30, the globular subunit of adipocyte complement-related protein of 30 kDa (ACRP30), improves insulin sensitivity and increases fatty acid oxidation. The mechanism by which gACRP30 exerts these effects is unknown. Here, we examined if gACRP30 activates AMP-activated protein kinase (AMPK), an en...

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Autors principals: Tomas, Eva, Tsao, Tsu-Shuen, Saha, Asish K., Murrey, Heather E., Zhang, Cheng cheng, Itani, Samar I., Lodish, Harvey F., Ruderman, Neil B.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC138607/
https://ncbi.nlm.nih.gov/pubmed/12456889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222657499
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