Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol’s Effects on Insulin Action in Rats

OBJECTIVE: Sirtuin 1 (SIRT1) and its activator resveratrol are emerging as major regulators of metabolic processes. We investigate the site of resveratrol action on glucose metabolism and the contribution of SIRT1 to these effects. Because the arcuate nucleus in the mediobasal hypothalamus (MBH) pla...

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Detalhes bibliográficos
Main Authors: Knight, Colette M., Gutierrez-Juarez, Roger, Lam, Tony K.T., Arrieta-Cruz, Isabel, Huang, Loli, Schwartz, Gary, Barzilai, Nir, Rossetti, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198094/
https://ncbi.nlm.nih.gov/pubmed/21896928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0987
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