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Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

Short-term overfeeding blunts the central effects of fatty acids on food intake and glucose production. This acquired defect in nutrient sensing could contribute to the rapid onset of hyperphagia and insulin resistance in this model. Here we examined whether central inhibition of lipid oxidation is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pocai, Alessandro, Lam, Tony K.T., Obici, Silvana, Gutierrez-Juarez, Roger, Muse, Evan D., Arduini, Arduino, Rossetti, Luciano
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395479/
https://ncbi.nlm.nih.gov/pubmed/16528412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26640
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