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Yin and Yang of hypothalamic insulin and leptin signaling in regulating white adipose tissue metabolism
Fatty acids released from white adipose tissue ( WAT) provide important energy substrates during fasting. However, uncontrolled fatty acid release from WAT during non-fasting states causes lipotoxicity and promotes inflammation and insulin resistance, which can lead to and worsen type 2 diabetes (DM...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253350/ https://ncbi.nlm.nih.gov/pubmed/21713385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11154-011-9190-4 |
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