Glucagon-Like Peptide 1/Glucagon Receptor Dual Agonism Reverses Obesity in Mice

OBJECTIVE: Oxyntomodulin (OXM) is a glucagon-like peptide 1 (GLP-1) receptor (GLP1R)/glucagon receptor (GCGR) dual agonist peptide that reduces body weight in obese subjects through increased energy expenditure and decreased energy intake. The metabolic effects of OXM have been attributed primarily...

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Detalhes bibliográficos
Main Authors: Pocai, Alessandro, Carrington, Paul E., Adams, Jennifer R., Wright, Michael, Eiermann, George, Zhu, Lan, Du, Xiaobing, Petrov, Aleksandr, Lassman, Michael E., Jiang, Guoqiang, Liu, Franklin, Miller, Corey, Tota, Laurie M., Zhou, Gaochao, Zhang, Xiaoping, Sountis, Michael M., Santoprete, Alessia, Capito', Elena, Chicchi, Gary G., Thornberry, Nancy, Bianchi, Elisabetta, Pessi, Antonello, Marsh, Donald J., SinhaRoy, Ranabir
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750209/
https://ncbi.nlm.nih.gov/pubmed/19602537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0278
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