GPR119 Agonism Increases Glucagon Secretion During Insulin-Induced Hypoglycemia

Insulin-induced hypoglycemia in diabetes is associated with impaired glucagon secretion. In this study, we tested whether stimulation of GPR119, a G-protein–coupled receptor expressed in pancreatic islet as well as enteroendocrine cells and previously shown to stimulate insulin and incretin secretio...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Li, Nina Xiaoyan, Brown, Stacey, Kowalski, Tim, Wu, Margaret, Yang, Liming, Dai, Ge, Petrov, Aleksandr, Ding, Yuyan, Dlugos, Tamara, Wood, Harold B., Wang, Liangsu, Erion, Mark, Sherwin, Robert, Kelley, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014553/
https://ncbi.nlm.nih.gov/pubmed/29669745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0031
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