GPR119 Agonism Increases Glucagon Secretion During Insulin-Induced Hypoglycemia

Insulin-induced hypoglycemia in diabetes is associated with impaired glucagon secretion. In this study, we tested whether stimulation of GPR119, a G-protein–coupled receptor expressed in pancreatic islet as well as enteroendocrine cells and previously shown to stimulate insulin and incretin secretio...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Li, Nina Xiaoyan, Brown, Stacey, Kowalski, Tim, Wu, Margaret, Yang, Liming, Dai, Ge, Petrov, Aleksandr, Ding, Yuyan, Dlugos, Tamara, Wood, Harold B., Wang, Liangsu, Erion, Mark, Sherwin, Robert, Kelley, David E.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2018
Fag:
Pharmacology and Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014553/
https://ncbi.nlm.nih.gov/pubmed/29669745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0031
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