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Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis
BACKGROUND: Experimental data indicate that reducing factor XI levels attenuates thrombosis without causing bleeding, but the role of factor XI in the prevention of postoperative venous thrombosis in humans is unknown. FXI-ASO (ISIS 416858) is a second-generation antisense oligonucleotide that speci...
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| Gepubliceerd in: | N Engl J Med |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367537/ https://ncbi.nlm.nih.gov/pubmed/25482425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1405760 |
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