Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice

Circulating transthyretin (TTR) is a critical determinant of plasma retinol-binding protein 4 (RBP4) levels. Elevated RBP4 levels cause insulin resistance, and the lowering of RBP4 levels improves glucose homeostasis. Since lowering TTR levels increases renal clearance of RBP4, we determined whether...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Diabetes
Autors principals: Zemany, Laura, Bhanot, Sanjay, Peroni, Odile D., Murray, Susan F., Moraes-Vieira, Pedro M., Castoldi, Angela, Manchem, Prasad, Guo, Shuling, Monia, Brett P., Kahn, Barbara B.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2015
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407860/
https://ncbi.nlm.nih.gov/pubmed/25524914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0970
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars