Antigen Presentation and T-Cell Activation Are Critical for RBP4-Induced Insulin Resistance

Adipose tissue (AT) inflammation contributes to impaired insulin action, which is a major cause of type 2 diabetes. RBP4 is an adipocyte- and liver-derived protein with an important role in insulin resistance, metabolic syndrome, and AT inflammation. RBP4 elevation causes AT inflammation by activati...

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Publicado en:Diabetes
Autores principales: Moraes-Vieira, Pedro M., Castoldi, Angela, Aryal, Pratik, Wellenstein, Kerry, Peroni, Odile D., Kahn, Barbara B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2016
Materias:
Immunology and Transplantation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839203/
https://ncbi.nlm.nih.gov/pubmed/26936962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1696
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