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Antisense oligonucleotide therapy for neurodegenerative disease
Neurotoxicity from accumulation of misfolded/mutant proteins is thought to drive pathogenesis in neurodegenerative diseases. Since decreasing levels of proteins responsible for such accumulations is likely to ameliorate disease, a therapeutic strategy has been developed to downregulate almost any ge...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1518790/ https://ncbi.nlm.nih.gov/pubmed/16878173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25424 |
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