β-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload

著者: Melchiori, Luca, Gardenghi, Sara, Rivella, Stefano
出版事項 2010

Anemia, Ineffective Erythropoiesis and Hepcidin: Interacting Factors in Abnormal Iron Metabolism Leading to Iron Overload in β-Thalassemia

著者: Gardenghi, Sara, Grady, Robert W., Rivella, Stefano
出版事項 2010

Iron metabolism and ineffective erythropoiesis in β-thalassemia mouse models

著者: Ramos, Pedro, Melchiori, Luca, Gardenghi, Sara, Van-Roijen, Nico, Grady, Robert W., Ginzburg, Yelena, Rivella, Stefano
出版事項 2010

Genetic loss of Tmprss6 alters terminal erythroid differentiation in a mouse model of β-thalassemia intermedia

著者: Stagg, David B., Whittlesey, Rebecca L., Li, Xiuqi, Lozovatsky, Larisa, Gardenghi, Sara, Rivella, Stefano, Finberg, Karin E.
出版年 Haematologica (2019)

Hepcidin and Hfe in iron overload in β-thalassemia

著者: Gardenghi, Sara, Ramos, Pedro, Follenzi, Antonia, Rao, Niva, Rachmilewitz, Eliezer A., Giardina, Patricia J., Grady, Robert W., Rivella, Stefano
出版事項 2010

Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice

著者: Guo, Shuling, Casu, Carla, Gardenghi, Sara, Booten, Sheri, Aghajan, Mariam, Peralta, Raechel, Watt, Andy, Freier, Sue, Monia, Brett P., Rivella, Stefano
出版事項 2013

Hepcidin inhibits Smad3 phosphorylation in hepatic stellate cells by impeding ferroportin-mediated regulation of Akt

著者: Han, Chang Yeob, Koo, Ja Hyun, Kim, Sung Hoon, Gardenghi, Sara, Rivella, Stefano, Strnad, Pavel, Hwang, Se Jin, Kim, Sang Geon
出版年 Nat Commun (2016)

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction

著者: Zuccato, Cristina, Breda, Laura, Salvatori, Francesca, Breveglieri, Giulia, Gardenghi, Sara, Bianchi, Nicoletta, Brognara, Eleonora, Lampronti, Ilaria, Borgatti, Monica, Rivella, Stefano, Gambari, Roberto
出版事項 2012

Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response

著者: Richardson, Chanté L., Delehanty, Lorrie L., Bullock, Grant C., Rival, Claudia M., Tung, Kenneth S., Kimpel, Donald L., Gardenghi, Sara, Rivella, Stefano, Goldfarb, Adam N.
出版事項 2013

Intestinal HIF2α promotes tissue-iron accumulation in disorders of iron overload with anemia

著者: Anderson, Erik R., Taylor, Matthew, Xue, Xiang, Ramakrishnan, Sadeesh K., Martin, Angelical, Xie, Liwei, Bredell, Bryce X., Gardenghi, Sara, Rivella, Stefano, Shah, Yatrik M.
出版事項 2013

Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus

著者: Gardenghi, Sara, Renaud, Tom M., Meloni, Alessandra, Casu, Carla, Crielaard, Bart J., Bystrom, Laura M., Greenberg-Kushnir, Noa, Sasu, Barbra J., Cooke, Keegan S., Rivella, Stefano
出版事項 2014

Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis

著者: Ramos, Pedro, Guy, Ella, Chen, Nan, Proenca, Catia C., Gardenghi, Sara, Casu, Carla, Follenzi, Antonia, Van Rooijen, Nico, Grady, Robert W., de Sousa, Maria, Rivella, Stefano
出版事項 2011

Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia

著者: Suragani, Rajasekhar N. V. S., Cawley, Sharon M., Li, Robert, Wallner, Samantha, Alexander, Mark J., Mulivor, Aaron W., Gardenghi, Sara, Rivella, Stefano, Grinberg, Asya V., Pearsall, R. Scott, Kumar, Ravindra
出版事項 2014

Therapeutic Hemoglobin Levels after Gene Transfer in β-Thalassemia Mice and in Hematopoietic Cells of β-Thalassemia and Sickle Cells Disease Patients

著者: Breda, Laura, Casu, Carla, Gardenghi, Sara, Bianchi, Nicoletta, Cartegni, Luca, Narla, Mohandas, Yazdanbakhsh, Karina, Musso, Marco, Manwani, Deepa, Little, Jane, Gardner, Lawrence B., Kleinert, Dorothy A., Prus, Eugenia, Fibach, Eitan, Grady, Robert W., Giardina, Patricia J., Gambari, Roberto, Rivella, Stefano
出版事項 2012

Macrophages support pathological erythropoiesis in Polycythemia Vera and Beta-Thalassemia

著者: Ramos, Pedro, Casu, Carla, Gardenghi, Sara, Breda, Laura, Crielaard, Bart J., Guy, Ella, Marongiu, Maria Franca, Gupta, Ritama, Levine, Ross L., Abdel-Wahab, Omar, Ebert, Benjamin L., Van Rooijen, Nico, Ghaffari, Saghi, Grady, Robert W., Giardina, Patricia J., Rivella, Stefano
出版事項 2013

Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells

著者: Bystrom, Laura M., Bezerra, Daniel P., Hsu, Hsiao-Ting, Zong, Hongliang, Lara-Martínez, Luis A., De Leon, Jeanne P., Emmanuel, Megan, Méry, David, Gardenghi, Sara, Hassane, Duane, Neto, Catherine C., Cunningham-Rundles, Susanna, Becker, Michael W., Rivella, Stefano, Guzman, Monica L.
出版年 Blood Adv (2019)

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

著者: Gardenghi, Sara, Ramos, Pedro, Marongiu, Maria Franca, Melchiori, Luca, Breda, Laura, Guy, Ella, Muirhead, Kristen, Rao, Niva, Roy, Cindy N., Andrews, Nancy C., Nemeth, Elizabeta, Follenzi, Antonia, An, Xiuli, Mohandas, Narla, Ginzburg, Yelena, Rachmilewitz, Eliezer A., Giardina, Patricia J., Grady, Robert W., Rivella, Stefano
出版事項 2010

HMGB1 Mediates Anemia of Inflammation in Murine Sepsis Survivors

著者: Valdés-Ferrer, Sergio I, Papoin, Julien, Dancho, Meghan E, Olofsson, Peder S, Li, Jianhua, Lipton, Jeffrey M, Avancena, Patricia, Yang, Huan, Zou, Yong-Rui, Chavan, Sangeeta S, Volpe, Bruce T, Gardenghi, Sara, Rivella, Stefano, Diamond, Betty, Andersson, Ulf, Steinberg, Bettie M, Blanc, Lionel, Tracey, Kevin J
出版年 Mol Med (2015)

Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

著者: Gardenghi, Sara, Marongiu, Maria F., Ramos, Pedro, Guy, Ella, Breda, Laura, Chadburn, Amy, Liu, YiFang, Amariglio, Ninette, Rechavi, Gideon, Rachmilewitz, Eliezer A., Breuer, William, Cabantchik, Z. Ioav, Wrighting, Diedra M., Andrews, Nancy C., de Sousa, Maria, Giardina, Patricia J., Grady, Robert W., Rivella, Stefano
出版事項 2007