Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response

The unique sensitivity of early red cell progenitors to iron deprivation, known as the erythroid iron restriction response, serves as a basis for human anemias globally. This response impairs erythropoietin-driven erythropoiesis and underlies erythropoietic repression in iron deficiency anemia. Mech...

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Bibliografski detalji
Glavni autori: Richardson, Chanté L., Delehanty, Lorrie L., Bullock, Grant C., Rival, Claudia M., Tung, Kenneth S., Kimpel, Donald L., Gardenghi, Sara, Rivella, Stefano, Goldfarb, Adam N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726169/
https://ncbi.nlm.nih.gov/pubmed/23863711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68487
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