Iron control of erythroid development by a novel aconitase-associated regulatory pathway

Human red cell differentiation requires the action of erythropoietin on committed progenitor cells. In iron deficiency, committed erythroid progenitors lose responsiveness to erythropoietin, resulting in hypoplastic anemia. To address the basis for iron regulation of erythropoiesis, we established p...

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Detalhes bibliográficos
Main Authors: Bullock, Grant C., Delehanty, Lorrie L., Talbot, Anne-Laure, Gonias, Sara L., Tong, Wing-Hang, Rouault, Tracey A., Dewar, Brian, Macdonald, Jeffrey M., Chruma, Jason J., Goldfarb, Adam N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904585/
https://ncbi.nlm.nih.gov/pubmed/20407036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-251496
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