Iron control of erythroid development by a novel aconitase-associated regulatory pathway

Human red cell differentiation requires the action of erythropoietin on committed progenitor cells. In iron deficiency, committed erythroid progenitors lose responsiveness to erythropoietin, resulting in hypoplastic anemia. To address the basis for iron regulation of erythropoiesis, we established p...

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Главные авторы: Bullock, Grant C., Delehanty, Lorrie L., Talbot, Anne-Laure, Gonias, Sara L., Tong, Wing-Hang, Rouault, Tracey A., Dewar, Brian, Macdonald, Jeffrey M., Chruma, Jason J., Goldfarb, Adam N.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2010
Предметы:
Red Cells, Iron, and Erythropoiesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904585/
https://ncbi.nlm.nih.gov/pubmed/20407036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-251496
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