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Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor

Iron-restricted human anemias are associated with the acquisition of marrow resistance to the hematopoietic cytokine erythropoietin (Epo). Regulation of Epo responsiveness by iron availability serves as the basis for intravenous iron therapy in anemias of chronic disease. Epo engagement of its recep...

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Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Khalil, Shadi, Delehanty, Lorrie, Grado, Stephen, Holy, Maja, White, Zollie, Freeman, Katie, Kurita, Ryo, Nakamura, Yukio, Bullock, Grant, Goldfarb, Adam
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789406/
https://ncbi.nlm.nih.gov/pubmed/29282252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170396
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