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A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2
Erythroid progenitors are the largest consumers of iron in the human body. In these cells, a high flux of iron must reach the mitochondrial matrix to form sufficient heme to support hemoglobinization. Canonical erythroid iron trafficking occurs via the first transferrin receptor (TfR1)-mediated endo...
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| Pubblicato in: | Blood Adv |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728310/ https://ncbi.nlm.nih.gov/pubmed/29296759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016003772 |
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