Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice

The mechanisms underlying thrombocytosis in patients with iron deficiency anemia remain unknown. Here, we present findings that support the hypothesis that low iron biases the commitment of megakaryocytic (Mk)-erythroid progenitors (MEPs) toward the Mk lineage in both human and mouse. In MEPs of tra...

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Bibliografski detalji
Izdano u:Blood
Glavni autori: Xavier-Ferrucio, Juliana, Scanlon, Vanessa, Li, Xiuqi, Zhang, Ping-Xia, Lozovatsky, Larisa, Ayala-Lopez, Nadia, Tebaldi, Toma, Halene, Stephanie, Cao, Chang, Fleming, Mark D., Finberg, Karin E., Krause, Diane S.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2019
Teme:
Red Cells, Iron, and Erythropoiesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839952/
https://ncbi.nlm.nih.gov/pubmed/31439541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002039
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