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Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor

Iron-restricted human anemias are associated with the acquisition of marrow resistance to the hematopoietic cytokine erythropoietin (Epo). Regulation of Epo responsiveness by iron availability serves as the basis for intravenous iron therapy in anemias of chronic disease. Epo engagement of its recep...

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Vydáno v:J Exp Med
Hlavní autoři: Khalil, Shadi, Delehanty, Lorrie, Grado, Stephen, Holy, Maja, White, Zollie, Freeman, Katie, Kurita, Ryo, Nakamura, Yukio, Bullock, Grant, Goldfarb, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789406/
https://ncbi.nlm.nih.gov/pubmed/29282252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170396
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