HMGB1 Mediates Anemia of Inflammation in Murine Sepsis Survivors

Patients surviving sepsis develop anemia, but the molecular mechanism is unknown. Here we observed that mice surviving polymicrobial gram-negative sepsis develop hypochromic, microcytic anemia with reticulocytosis. The bone marrow of sepsis survivors accumulates polychromatophilic and orthochromatic...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Med
Auteurs principaux: Valdés-Ferrer, Sergio I, Papoin, Julien, Dancho, Meghan E, Olofsson, Peder S, Li, Jianhua, Lipton, Jeffrey M, Avancena, Patricia, Yang, Huan, Zou, Yong-Rui, Chavan, Sangeeta S, Volpe, Bruce T, Gardenghi, Sara, Rivella, Stefano, Diamond, Betty, Andersson, Ulf, Steinberg, Bettie M, Blanc, Lionel, Tracey, Kevin J
Format: Artigo
Langue:Inglês
Publié: The Feinstein Institute Press 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818261/
https://ncbi.nlm.nih.gov/pubmed/26736178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00243
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires