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The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation
BACKGROUND: Extra-corpuscular hemoglobin is an endogenous factor enhancing inflammatory tissue damage, a process counteracted by the hemoglobin-binding plasma protein haptoglobin composed of alpha and beta subunits connected by disulfide bridges. Recent studies established that haptoglobin also bind...
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| Publicado no: | J Intern Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5477782/ https://ncbi.nlm.nih.gov/pubmed/28464519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12619 |
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