Challenges and Therapeutic Opportunities of Autophagy in Cancer Therapy

by Silva, Valdenizia R., Neves, Sara P., Santos, Luciano de S., Dias, Rosane B., Bezerra, Daniel P.
Published in Cancers (Basel) (2020)

Nucleobase Derivatives as Building Blocks to Form Ru(II)-Based Complexes with High Cytotoxicity

by Carvalho, Diogo E. L., Oliveira, Katia M., Bomfim, Larissa M., Soares, Milena B. P., Bezerra, Daniel P., Batista, Alzir A., Correa, Rodrigo S.
Published in ACS Omega (2020)

Semi-synthesis of β-keto-1,2,3-triazole derivatives from ethinylestradiol and evaluation of the cytotoxic activity

by Queiroz, Thayane M., Orozco, Erika V.M., Silva, Valdenizia R., Santos, Luciano S., Soares, Milena B.P., Bezerra, Daniel P., Porto, André L.M.
Published in Heliyon (2019)

Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling

by Silva, Suellen L. R., Baliza, Ingrid R. S., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Correa, Rodrigo S., Batista, Alzir A., Bezerra, Daniel P.
Published in Sci Rep (2019)

Ruthenium(II) complexes with 6-methyl-2-thiouracil selectively reduce cell proliferation, cause DNA double-strand break and trigger caspase-mediated apoptosis through JNK/p38 pathw...

by Bomfim, Larissa M., de Araujo, Fênix A., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Correa, Rodrigo S., Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.
Published in Sci Rep (2019)

A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human ac...

by Oliveira, Maiara de S., Barbosa, Marília I.F., de Souza, Thiago Belarmino, Moreira, Diogo R.M., Martins, Felipe Terra, Villarreal, Wilmer, Machado, Rafael P., Doriguetto, Antônio Carlos, Soares, Milena B.P., Bezerra, Daniel P.
Published in Redox Biol (2018)

Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Mo...

by Baliza, Ingrid R. S., Silva, Suellen L. R., Santos, Luciano de S., Neto, João H. Araujo, Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.
Published in Front Oncol (2019)

Benzylated Dihydroflavones and Isoquinoline-Derived Alkaloids from the Bark of Diclinanona calycina (Annonaceae) and Their Cytotoxicities

by Costa, Emmanoel V., Soares, Liviane do N., Chaar, Jamal da Silva, Silva, Valdenizia R., Santos, Luciano de S., Koolen, Hector H. F., da Silva, Felipe M. A., Tavares, Josean F., Zengin, Gokhan, Soares, Milena B. P., Bezerra, Daniel P.
Published in Molecules (2021)

Ruthenium Complexes Containing Heterocyclic Thioamidates Trigger Caspase-Mediated Apoptosis Through MAPK Signaling in Human Hepatocellular Carcinoma Cells

by Neves, Sara P., de Carvalho, Nanashara C., da Silva, Monize M., Rodrigues, Ana Carolina B. C., Bomfim, Larissa M., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.
Published in Front Oncol (2019)

Docking, Synthesis and Antiproliferative Activity of N-Acylhydrazone Derivatives Designed as Combretastatin A4 Analogues

by do Amaral, Daniel Nascimento, Cavalcanti, Bruno C., Bezerra, Daniel P., Ferreira, Paulo Michel P., Castro, Rosane de Paula, Sabino, José Ricardo, Machado, Camila Maria Longo, Chammas, Roger, Pessoa, Claudia, Sant'Anna, Carlos M. R., Barreiro, Eliezer J., Lima, Lídia Moreira
Published 2014

Cytotoxic potential of selected medicinal plants in northeast Brazil

by da Silva, Thiago B. C., Costa, Cinara O. D’Sousa, Galvão, Alexandre F. C., Bomfim, Larissa M., Rodrigues, Ana Carolina B. da C., Mota, Mauricio C. S., Dantas, Alex A., dos Santos, Tiago R., Soares, Milena B. P., Bezerra, Daniel P.
Published in BMC Complement Altern Med (2016)

Cytotoxic Alkaloids from the Stem of Xylopia laevigata

by Menezes, Leociley R. A., Costa, Cinara O. D´Sousa, Rodrigues, Ana Carolina B. da C., Santo, Felipe R. do E., Nepel, Angelita, Dutra, Lívia M., Silva, Felipe M. A., Soares, Milena B. P., Barison, Andersson, Costa, Emmanoel V., Bezerra, Daniel P.
Published in Molecules (2016)

Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells

by Bystrom, Laura M., Bezerra, Daniel P., Hsu, Hsiao-Ting, Zong, Hongliang, Lara-Martínez, Luis A., De Leon, Jeanne P., Emmanuel, Megan, Méry, David, Gardenghi, Sara, Hassane, Duane, Neto, Catherine C., Cunningham-Rundles, Susanna, Becker, Michael W., Rivella, Stefano, Guzman, Monica L.
Published in Blood Adv (2019)

Biological and physical approaches on the role of piplartine (piperlongumine) in cancer

by Henrique, Tiago, Zanon, Caroline de F., Girol, Ana P., Stefanini, Ana Carolina Buzzo, Contessoto, Nayara S. de A., da Silveira, Nelson J. F., Bezerra, Daniel P., Silveira, Edilberto R., Barbosa-Filho, José M., Cornélio, Marinonio L., Oliani, Sonia M., Tajara, Eloiza H.
Published in Sci Rep (2020)

A novel ruthenium complex with xanthoxylin induces S-phase arrest and causes ERK1/2-mediated apoptosis in HepG2 cells through a p53-independent pathway

by de Carvalho, Nanashara C., Neves, Sara P., Dias, Rosane B., Valverde, Ludmila de F., Sales, Caroline B. S., Rocha, Clarissa A. G., Soares, Milena B. P., dos Santos, Edjane R., Oliveira, Regina M. M., Carlos, Rose M., Nogueira, Paulo C. L., Bezerra, Daniel P.
Published in Cell Death Dis (2018)

Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells

by D’Sousa Costa, Cinara O., Araujo Neto, João H., Baliza, Ingrid R.S., Dias, Rosane B., Valverde, Ludmila de F., Vidal, Manuela T.A., Sales, Caroline B.S., Rocha, Clarissa A.G., Moreira, Diogo R.M., Soares, Milena B.P., Batista, Alzir A., Bezerra, Daniel P.
Published in Oncotarget (2017)

Antitumor Effect of the Essential Oil from the Leaves of Croton matourensis Aubl. (Euphorbiaceae)

by de Lima, Emilly J. S. P., Alves, Rafaela G., D´Elia, Gigliola M. A., da Anunciação, Talita A., Silva, Valdenizia R., Santos, Luciano de S., Soares, Milena B. P., Cardozo, Nállarett M. D., Costa, Emmanoel V., da Silva, Felipe M. A., Koolen, Hector H. F., Bezerra, Daniel P.
Published in Molecules (2018)

Cyperus articulatus L. (Cyperaceae) Rhizome Essential Oil Causes Cell Cycle Arrest in the G(2)/M Phase and Cell Death in HepG2 Cells and Inhibits the Development of Tumors in a Xen...

by Nogueira, Mateus L., de Lima, Emilly J. S. P., Adrião, Asenate A. X., Fontes, Sheila S., Silva, Valdenizia R., Santos, Luciano de S., Soares, Milena B. P., Dias, Rosane B., Rocha, Clarissa A. Gurgel, Costa, Emmanoel V., da Silva, Felipe M. A., Vannier-Santos, Marcos A., Cardozo, Nállarett M. D., Koolen, Hector H. F., Bezerra, Daniel P.
Published in Molecules (2020)