Sirtuins in mammals: insights into their biological function

Por MICHAN, Shaday, SINCLAIR, David
Publicado em 2007

Asexual Development Is Increased in Neurospora crassa cat-3-Null Mutant Strains

Por Michán, Shaday, Lledías, Fernando, Hansberg, Wilhelm
Publicado em 2003

Increasing NAD Synthesis in Muscle via Nicotinamide Phosphoribosyltransferase Is Not Sufficient to Promote Oxidative Metabolism

Por Frederick, David W., Davis, James G., Dávila, Antonio, Agarwal, Beamon, Michan, Shaday, Puchowicz, Michelle A., Nakamaru-Ogiso, Eiko, Baur, Joseph A.
Publicado no J Biol Chem (2015)

Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

Por Palacios, Orsolya M., Carmona, Juan J., Michan, Shaday, Chen, Ke Yun, Manabe, Yasuko, III, Jack Lee Ward, Goodyear, Laurie J., Tong, Qiang
Publicado em 2009

SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance

Por Ramadori, Giorgio, Fujikawa, Teppei, Anderson, Jason, Berglund, Eric D., Frazao, Renata, Michan, Shaday, Vianna, Claudia R., Sinclair, David A., Elias, Carol F., Coppari, Roberto
Publicado em 2011

Sirtuin1 Over-Expression Does Not Impact Retinal Vascular and Neuronal Degeneration in a Mouse Model of Oxygen-Induced Retinopathy

Por Michan, Shaday, Juan, Aimee M., Hurst, Christian G., Cui, Zhenghao, Evans, Lucy P., Hatton, Colman J., Pei, Dorothy T., Ju, Meihua, Sinclair, David A., Smith, Lois E. H., Chen, Jing
Publicado em 2014

The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

Por Firestein, Ron, Blander, Gil, Michan, Shaday, Oberdoerffer, Philipp, Ogino, Shuji, Campbell, Jennifer, Bhimavarapu, Anupama, Luikenhuis, Sandra, de Cabo, Rafael, Fuchs, Charles, Hahn, William C., Guarente, Leonard P., Sinclair, David A.
Publicado em 2008

Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling

Por Beirowski, Bogdan, Gustin, Jason, Armour, Sean M., Yamamoto, Hiroyasu, Viader, Andreu, North, Brian J., Michán, Shaday, Baloh, Robert H., Golden, Judy P., Schmidt, Robert E., Sinclair, David A., Auwerx, Johan, Milbrandt, Jeffrey
Publicado em 2011

Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy

Por Chen, Jing, Michan, Shaday, Juan, Aimee M., Hurst, Christian G., Hatton, Colman J., Pei, Dorothy T., Joyal, Jean-Sebastien, Evans, Lucy P., Cui, Zhenghao, Stahl, Andreas, Sapieha, Przemyslaw, Sinclair, David A., Smith, Lois E. H.
Publicado em 2013

Resveratrol Inhibits Pathologic Retinal Neovascularization in Vldlr(−/−) Mice

Por Hua, Jing, Guerin, Karen I., Chen, Jing, Michán, Shaday, Stahl, Andreas, Krah, Nathan M., Seaward, Molly R., Dennison, Roberta J., Juan, Aimee M., Hatton, Colman J., Sapieha, Przemyslaw, Sinclair, David A., Smith, Lois E. H.
Publicado em 2011

SIRT2 induces the checkpoint kinase BubR1 to increase lifespan

Por North, Brian J, Rosenberg, Michael A, Jeganathan, Karthik B, Hafner, Angela V, Michan, Shaday, Dai, Jing, Baker, Darren J, Cen, Yana, Wu, Lindsay E, Sauve, Anthony A, van Deursen, Jan M, Rosenzweig, Anthony, Sinclair, David A
Publicado em 2014

Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice

Por Franco, Sara Santos, De Falco, Luigia, Ghaffari, Saghi, Brugnara, Carlo, Sinclair, David A., Matte’, Alessandro, Iolascon, Achille, Mohandas, Narla, Bertoldi, Mariarita, An, Xiuli, Siciliano, Angela, Rimmelé, Pauline, Cappellini, Maria Domenica, Michan, Shaday, Zoratti, Elisa, Anne, Janin, De Franceschi, Lucia
Publicado em 2014

DNA damage-induced alterations in chromatin contribute to genomic integrity and age-related changes in gene expression

Por Oberdoerffer, Philipp, Michan, Shaday, McVay, Michael, Mostoslavsky, Raul, Vann, James, Park, Sang-Kyu, Hartlerode, Andrea, Stegmuller, Judith, Hafner, Angela, Loerch, Patrick, Wright, Sarah M., Mills, Kevin D., Bonni, Azad, Yankner, Bruce A., Scully, Ralph, Prolla, Tomas A., Alt, Frederick W., Sinclair, David A.
Publicado em 2008

SIRT1 Is Essential for Normal Cognitive Function and Synaptic Plasticity

Por Michán, Shaday, Li, Ying, Chou, Maggie Meng-Hsiu, Parrella, Edoardo, Ge, Huanying, Long, Jeffrey M., Allard, Joanne S., Lewis, Kaitlyn, Miller, Marshall, Xu, Wei, Mervis, Ronald F., Chen, Jing, Guerin, Karen I., Smith, Lois E. H., McBurney, Michael W., Sinclair, David A., Baudry, Michel, de Cabo, Rafael, Longo, Valter D.
Publicado em 2010

Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

Por Hubbard, Basil P., Gomes, Ana P., Dai, Han, Li, Jun, Case, April W., Considine, Thomas, Riera, Thomas V., Lee, Jessica E., Sook Yen, E, Lamming, Dudley W., Pentelute, Bradley L., Schuman, Eli R., Stevens, Linda A., Ling, Alvin J. Y., Armour, Sean M., Michan, Shaday, Zhao, Huizhen, Jiang, Yong, Sweitzer, Sharon M., Blum, Charles A., Disch, Jeremy S., Ng, Pui Yee, Howitz, Konrad T., Rolo, Anabela P., Hamuro, Yoshitomo, Moss, Joel, Perni, Robert B., Ellis, James L., Vlasuk, George P., Sinclair, David A.
Publicado em 2013