Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling

The formation of myelin by Schwann cells (SCs) occurs via a series of orchestrated molecular events. We previously used global expression profiling to examine peripheral nerve myelination and identified the NAD(+)-dependent deacetylase Sir-two-homolog 2 (Sirt2) as a protein likely to be involved in...

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Bibliografiske detaljer
Main Authors: Beirowski, Bogdan, Gustin, Jason, Armour, Sean M., Yamamoto, Hiroyasu, Viader, Andreu, North, Brian J., Michán, Shaday, Baloh, Robert H., Golden, Judy P., Schmidt, Robert E., Sinclair, David A., Auwerx, Johan, Milbrandt, Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203793/
https://ncbi.nlm.nih.gov/pubmed/21949390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104969108
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