Studying the Replicative Life Span of Yeast Cells

Por Sinclair, David A.
Publicado no Methods Mol Biol (2013)

Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase

Por Cohen, Haim, Sinclair, David A.
Publicado em 2001

Xenohormesis: Sensing the Chemical Cues of Other Species

Por Howitz, Konrad T., Sinclair, David A.
Publicado em 2008

Small-Molecule Allosteric Activators of Sirtuins

Por Sinclair, David A., Guarente, Leonard
Publicado em 2013

Oogonial stem cells as a model to study age-associated infertility in women

Por Garg, Neha, Sinclair, David A.
Publicado no Reprod Fertil Dev (2015)

Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds

Por Bonkowski, Michael S., Sinclair, David A.
Publicado no Nat Rev Mol Cell Biol (2016)

Sirtuins: a conserved key unlocking AceCS activity

Por North, Brian J., Sinclair, David A.
Publicado em 2006

Mammalian Sirtuins: Biological Insights and Disease Relevance

Por Haigis, Marcia C., Sinclair, David A.
Publicado em 2010

The Intersection Between Aging and Cardiovascular Disease

Por North, Brian J., Sinclair, David A.
Publicado em 2012

Germline energetics, aging and female infertility

Por Tilly, Jonathan L., Sinclair, David A.
Publicado em 2013

Small molecule SIRT1 activators for the treatment of aging and age-related diseases

Por Hubbard, Basil P., Sinclair, David A.
Publicado em 2014

SIRT2 controls the pentose phosphate switch

Por Wu, Lindsay E, Sinclair, David A
Publicado em 2014

When stem cells grow old: phenotypes and mechanisms of stem cell aging

Por Schultz, Michael B., Sinclair, David A.
Publicado no Development (2016)

Measurement of Sirtuin Enzyme Activity Using a Substrate-Agnostic Fluorometric Nicotinamide Assay

Por Hubbard, Basil P., Sinclair, David A.
Publicado no Methods Mol Biol (2013)

What is Xenohormesis?

Por Baur, Joseph A., Sinclair, David A.
Publicado no Am J Pharmacol Toxicol (2008)

Restoring stem cells — all you need is NAD(+)

Por Wu, Lindsay E, Sinclair, David A
Publicado no Cell Res (2016)

Why NAD(+) Declines during Aging: It’s Destroyed

Por Schultz, Michael B., Sinclair, David A.
Publicado no Cell Metab (2016)

Nampt/PBEF/Visfatin: A regulator of mammalian health and longevity?

Por Yang, Hongying, Lavu, Siva, Sinclair, David A.
Publicado em 2006

Longevity Regulation in Saccharomyces cerevisiae: Linking Metabolism, Genome Stability, and Heterochromatin

Por Bitterman, Kevin J., Medvedik, Oliver, Sinclair, David A.
Publicado em 2003

Aging: past, present and future

Por Blagosklonny, Mikhail V., Campisi, Judith, Sinclair, David A.
Publicado em 2009