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Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD(+))-dependent deacylases with remarkable abilities to prevent diseases and even reverse aspects of ageing. Mice engineered to express additional copies of SIRT1 or SIRT6, or treated with sirtuin-activating compounds (STACs...
Gardado en:
| Publicado en: | Nat Rev Mol Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5107309/ https://ncbi.nlm.nih.gov/pubmed/27552971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2016.93 |
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