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Epigenetic changes during aging and their reprogramming potential
The aging process results in significant epigenetic changes at all levels of chromatin and DNA organization. These include reduced global heterochromatin, nucleosome remodeling and loss, changes in histone marks, global DNA hypomethylation with CpG island hypermethylation, and the relocalization of...
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| Publicado no: | Crit Rev Biochem Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6424622/ https://ncbi.nlm.nih.gov/pubmed/30822165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2019.1570075 |
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