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INVESTIGATING THE DNA DAMAGE RESPONSE AS A DRIVER OF EPIGENETIC CHANGE DURING AGING
Mutations were first posited as a root cause of aging over 60 years ago. Consistent with this idea, exposure to DNA damaging agents, such as UV light on skin, accelerates aspects of aging. Similarly, defects in DNA repair are seen in progeroid syndromes. Over the past 30 years, however, there have b...
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| Publicat a: | Innov Aging |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6239361/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy031.3296 |
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