The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

Numerous longevity genes have been discovered in model organisms and altering their function results in prolonged lifespan. In mammals, some have speculated that any health benefits derived from manipulating these same pathways might be offset by increased cancer risk on account of their propensity...

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Détails bibliographiques
Auteurs principaux: Firestein, Ron, Blander, Gil, Michan, Shaday, Oberdoerffer, Philipp, Ogino, Shuji, Campbell, Jennifer, Bhimavarapu, Anupama, Luikenhuis, Sandra, de Cabo, Rafael, Fuchs, Charles, Hahn, William C., Guarente, Leonard P., Sinclair, David A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289879/
https://ncbi.nlm.nih.gov/pubmed/18414679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002020
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