SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance

Chronic feeding on high-calorie diets causes obesity and type 2 diabetes mellitus (T2DM), illnesses that affect hundreds of millions. Thus, understanding the pathways protecting against diet-induced metabolic imbalance is of paramount medical importance. Here we show that mice lacking SIRT1 in stero...

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Autores principales: Ramadori, Giorgio, Fujikawa, Teppei, Anderson, Jason, Berglund, Eric D., Frazao, Renata, Michan, Shaday, Vianna, Claudia R., Sinclair, David A., Elias, Carol F., Coppari, Roberto
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172583/
https://ncbi.nlm.nih.gov/pubmed/21907137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.06.014
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