SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity

Feeding on high-calorie (HC) diets induces serious metabolic imbalances, including obesity. Understanding the mechanisms against excessive body weight gain is critical for developing effective anti-obesity strategies. Here, we show that lack of nicotinamide adenosine dinucleotide (NAD(+))-dependent...

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Detalhes bibliográficos
Main Authors: Ramadori, Giorgio, Fujikawa, Teppei, Fukuda, Makoto, Anderson, Jason, Morgan, Donald A., Mostoslavsky, Raul, Stuart, Ronald C., Perello, Mario, Vianna, Claudia R., Nillni, Eduardo A., Rahmouni, Kamal, Coppari, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904327/
https://ncbi.nlm.nih.gov/pubmed/20620997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.05.010
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