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SIRT3 deacetylase: the Jekyll and Hyde sirtuin
Mitochondrial deacetylase SIRT3 protects against oxidative damage. In an article published online this month in EMBO reports, it is shown to also aggravate paracetamol-induced liver toxicity, calling for caution in trying to pharmacologically enhance SIRT3 activity.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147273/ https://ncbi.nlm.nih.gov/pubmed/21738223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.147 |
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