SIRT1 Promotes Differentiation of Normal Human Keratinocytes

Sir2 regulates lifespan in model organisms, which has stimulated interest in understanding human Sir2 homolog functions. The human Sir2 gene family comprises seven members (SIRT1–SIRT7). SIRT1, the human ortholog of the yeast Sir2 by closest sequence similarity, is a nicotinamide adenine dinucleotid...

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Main Authors: Blander, Gil, Bhimavarapu, Anupama, Mammone, Thomas, Maes, Daniel, Elliston, Keith, Reich, Christian, Matsui, Mary Steidl, Guarente, Leonard, Loureiro, Joseph Jorge
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526938/
https://ncbi.nlm.nih.gov/pubmed/18563176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.179
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