Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

SIRT3 is a member of the sirtuin family of NAD(+)-dependent deacetylases, which is localized to the mitochondria and is enriched in kidney, brown adipose tissue, heart, and other metabolically active tissues. We report here that SIRT3 responds dynamically to both exercise and nutritional signals in...

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Bibliographic Details
Main Authors: Palacios, Orsolya M., Carmona, Juan J., Michan, Shaday, Chen, Ke Yun, Manabe, Yasuko, III, Jack Lee Ward, Goodyear, Laurie J., Tong, Qiang
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815736/
https://ncbi.nlm.nih.gov/pubmed/20157566
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