Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

SIRT3 is a member of the sirtuin family of NAD(+)-dependent deacetylases, which is localized to the mitochondria and is enriched in kidney, brown adipose tissue, heart, and other metabolically active tissues. We report here that SIRT3 responds dynamically to both exercise and nutritional signals in...

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Hlavní autoři: Palacios, Orsolya M., Carmona, Juan J., Michan, Shaday, Chen, Ke Yun, Manabe, Yasuko, III, Jack Lee Ward, Goodyear, Laurie J., Tong, Qiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815736/
https://ncbi.nlm.nih.gov/pubmed/20157566
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