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PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

PURPOSE OF THE REVIEW: PGC-1α has been extensively described as a master regulator of mitochondrial biogenesis. However, PGC-1α activity is not constant, and can be finely tuned in response to different metabolic situations. From this point of view, PGC-1α could be described as a mediator of the tra...

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Detalhes bibliográficos
Main Authors: Cantó, Carles, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627054/
https://ncbi.nlm.nih.gov/pubmed/19276888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOL.0b013e328328d0a4
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