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Caloric restriction, SIRT1 and longevity

More than 70 years after its initial report, caloric restriction stands strong as the most consistent non-pharmacological intervention increasing lifespan and protecting against metabolic disease. Among the different mechanisms by which caloric restriction may act, Sir2/SIRT1 (Silent information reg...

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Detalhes bibliográficos
Main Authors: Cantó, Carles, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627124/
https://ncbi.nlm.nih.gov/pubmed/19713122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2009.03.008
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