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Calorie restriction: is AMPK as a key sensor and effector?

Dietary restriction can extend lifespan in most organisms tested to date, suggesting that mechanisms sensing nutrient and energy availability might regulate longevity. The AMP-activated protein kinase (AMPK) has emerged as a key energy sensor with the ability to transcriptionally reprogram the cell...

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Detalhes bibliográficos
Main Authors: Cantó, Carles, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627048/
https://ncbi.nlm.nih.gov/pubmed/21841070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00010.2011
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