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Calorie restriction: is AMPK as a key sensor and effector?
Dietary restriction can extend lifespan in most organisms tested to date, suggesting that mechanisms sensing nutrient and energy availability might regulate longevity. The AMP-activated protein kinase (AMPK) has emerged as a key energy sensor with the ability to transcriptionally reprogram the cell...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627048/ https://ncbi.nlm.nih.gov/pubmed/21841070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00010.2011 |
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