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Caloric restriction, SIRT1 and longevity

More than 70 years after its initial report, caloric restriction stands strong as the most consistent non-pharmacological intervention increasing lifespan and protecting against metabolic disease. Among the different mechanisms by which caloric restriction may act, Sir2/SIRT1 (Silent information reg...

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Hlavní autoři: Cantó, Carles, Auwerx, Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627124/
https://ncbi.nlm.nih.gov/pubmed/19713122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2009.03.008
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