Sirtuin1 Over-Expression Does Not Impact Retinal Vascular and Neuronal Degeneration in a Mouse Model of Oxygen-Induced Retinopathy

Proliferative retinopathy is a leading cause of blindness, including retinopathy of prematurity (ROP) in children and diabetic retinopathy in adults. Retinopathy is characterized by an initial phase of vessel loss, leading to tissue ischemia and hypoxia, followed by sight threatening pathologic neov...

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Detalhes bibliográficos
Main Authors: Michan, Shaday, Juan, Aimee M., Hurst, Christian G., Cui, Zhenghao, Evans, Lucy P., Hatton, Colman J., Pei, Dorothy T., Ju, Meihua, Sinclair, David A., Smith, Lois E. H., Chen, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885684/
https://ncbi.nlm.nih.gov/pubmed/24416337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085031
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