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Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity

Oxygen administration to immature neonates suppresses VEGF-A expression in the retina, resulting in the catastrophic vessel loss that initiates retinopathy of prematurity. To investigate the mechanisms responsible for survival of blood vessels in the developing retina, we characterized two VEGF-A re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shih, Shu-Ching, Ju, Meihua, Liu, Nan, Smith, Lois E.H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162289/
https://ncbi.nlm.nih.gov/pubmed/12840058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317808
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