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Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity

Oxygen administration to immature neonates suppresses VEGF-A expression in the retina, resulting in the catastrophic vessel loss that initiates retinopathy of prematurity. To investigate the mechanisms responsible for survival of blood vessels in the developing retina, we characterized two VEGF-A re...

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Autori principali: Shih, Shu-Ching, Ju, Meihua, Liu, Nan, Smith, Lois E.H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC162289/
https://ncbi.nlm.nih.gov/pubmed/12840058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317808
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