The effects of intramolecular and intermolecular electrostatic repulsions on the stability and aggregation of NISTmAb revealed by HDX‐MS, DSC, and nanoDSF

por Hamuro, Yoshitomo, Derebe, Mehabaw Getahun, Venkataramani, Sathya, Nemeth, Jennifer F.
Publicado en Protein Sci (2021)

Quantitative Assessment of Protein Structural Models by Comparison of H/D Exchange MS Data with Exchange Behavior Accurately Predicted by DXCOREX

por Liu, Tong, Pantazatos, Dennis, Li, Sheng, Hamuro, Yoshitomo, Hilser, Vincent J., Woods, Virgil L.
Publicado 2011

Hydrogen-Deuterium Exchange Mass Spectrometry for Investigation of Backbone Dynamics of Oxidized and Reduced Cytochrome P450(cam)

por Hamuro, Yoshitomo, Molnar, Kathleen S., Coales, Stephen J., OuYang, Bo, Simorellis, Alana, Pochapsky, Thomas C.
Publicado 2007

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

por Chandra, Vikas, Huang, Pengxiang, Hamuro, Yoshitomo, Raghuram, Srilatha, Wang, Yongjun, Burris, Thomas P., Rastinejad, Fraydoon
Publicado 2008

Dissecting interdomain communication within cAPK regulatory subunit type IIβ using enhanced amide hydrogen/deuterium exchange mass spectrometry (DXMS)

por Zawadzki, Kerri M., Hamuro, Yoshitomo, Kim, Jack S., Garrod, Siv, Stranz, David D., Taylor, Susan S., Woods, Virgil L.
Publicado 2003

Local Conformational Stability of HIV-1 gp120 in Unliganded and CD4-Bound States as Defined by Amide Hydrogen/Deuterium Exchange

por Kong, Leopold, Huang, Chih-chin, Coales, Stephen J., Molnar, Kathleen S., Skinner, Jeff, Hamuro, Yoshitomo, Kwong, Peter D.
Publicado 2010

Rapid Analysis of Protein Structure and Dynamics by Hydrogen/Deuterium Exchange Mass Spectrometry

por Hamuro, Yoshitomo, Coales, Stephen J., Southern, Mark R., Nemeth-Cawley, Jennifer F., Stranz, David D., Griffin, Patrick R.
Publicado 2003

Protein structure change studied by hydrogen-deuterium exchange, functional labeling, and mass spectrometry

por Englander, Joan J., Del Mar, Charyl, Li, Will, Englander, S. Walter, Kim, Jack S., Stranz, David D., Hamuro, Yoshitomo, Woods, Virgil L.
Publicado 2003

Hydrogen/deuterium-exchange (H/D-Ex) of PPARγ LBD in the presence of various modulators

por Hamuro, Yoshitomo, Coales, Stephen J., Morrow, Jeffrey A., Molnar, Kathleen S., Tuske, Steven J., Southern, Mark R., Griffin, Patrick R.
Publicado 2006

Isofagomine Induced Stabilization of Glucocerebrosidase

por Kornhaber, Gregory J., Tropak, Michael B., Maegawa, Gustavo H., Tuske, Steven J., Coales, Stephen J., Mahuran, Don J., Hamuro, Yoshitomo
Publicado 2008

Distinct interaction modes of an AKAP bound to two regulatory subunit isoforms of protein kinase A revealed by amide hydrogen/deuterium exchange

por Burns-Hamuro, Lora L., Hamuro, Yoshitomo, Kim, Jack S., Sigala, Paul, Fayos, Rosa, Stranz, David D., Jennings, Patricia A., Taylor, Susan S., Woods, Virgil L.
Publicado 2005

Dynamic Structural Changes During Complement C3 Activation Analyzed by Hydrogen/Deuterium Exchange Mass Spectrometry

por Schuster, Michael C., Ricklin, Daniel, Papp, Krisztián, Molnar, Kathleen S., Coales, Stephen J., Hamuro, Yoshitomo, Sfyroera, Georgia, Chen, Hui, Winters, Michael S., Lambris, John D.
Publicado 2008

A Common Property of Amyotrophic Lateral Sclerosis-associated Variants: DESTABILIZATION OF THE COPPER/ZINC SUPEROXIDE DISMUTASE ELECTROSTATIC LOOP

por Molnar, Kathleen S., Karabacak, N. Murat, Johnson, Joshua L., Wang, Qi, Tiwari, Ashutosh, Hayward, Lawrence J., Coales, Stephen J., Hamuro, Yoshitomo, Agar, Jeffrey N.
Publicado 2009

Characterization of Pre-F-GCN4t, a Modified Human Respiratory Syncytial Virus Fusion Protein Stabilized in a Noncleaved Prefusion Conformation

por Blais, Normand, Gagné, Martin, Hamuro, Yoshitomo, Rheault, Patrick, Boyer, Martine, Steff, Ann-Muriel, Baudoux, Guy, Dewar, Vincent, Demers, Josée, Ruelle, Jean-Louis, Martin, Denis
Publicado en J Virol (2017)

Characterization of the complex formed between a potent neutralizing ovine-derived polyclonal anti-TNFα Fab fragment and human TNFα

por Abbott, W. Mark, Snow, Melanie, Eckersley, Sonia, Renshaw, Jonathan, Davies, Gareth, Norman, Richard A., Ceuppens, Peter, Slootstra, Jerry, Benschop, Joris J., Hamuro, Yoshitomo, Lee, Jessica E., Newham, Peter
Publicado 2013

Identification and Characterization of Ambroxol as an Enzyme Enhancement Agent for Gaucher Disease

por Maegawa, Gustavo H. B., Tropak, Michael B., Buttner, Justin D., Rigat, Brigitte A., Fuller, Maria, Pandit, Deepangi, Tang, Liangiie, Kornhaber, Gregory J., Hamuro, Yoshitomo, Clarke, Joe T. R., Mahuran, Don J.
Publicado 2009

Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes

por O'Shannessy, Daniel J., Somers, Elizabeth B., Albone, Earl, Cheng, Xin, Park, Young Chul, Tomkowicz, Brian E., Hamuro, Yoshitomo, Kohl, Thomas O., Forsyth, Tracy M., Smale, Robert, Fu, Yao-Shi, Nicolaides, Nicholas C.
Publicado 2011

Identification of Pharmacological Chaperones for Gaucher Disease and Characterization of Their Effects on β-Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry

por Tropak, Michael B., Kornhaber, Gregory J., Rigat, Brigitte A., Maegawa, Gustavo H., Buttner, Justin D., Blanchard, Jan E., Murphy, Cecilia, Tuske, Steven J., Coales, Stephen J., Hamuro, Yoshitomo, Brown, Eric D., Mahuran, Don J.
Publicado 2008

Construct Optimization for Protein NMR Structure Analysis Using Amide Hydrogen / Deuterium Exchange Mass Spectrometry

por Sharma, Seema, Zheng, Haiyan, Huang, Yuanpeng J., Ertekin, Asli, Hamuro, Yoshitomo, Rossi, Paolo, Tejero, Roberto, Acton, Thomas B., Xiao, Rong, Jiang, Mei, Zhao, Li, Ma, Li-Chung, Swapna, G. V. T., Aramini, James M., Montelione, Gaetano T.
Publicado 2009

Crystallographic structure of a small molecule SIRT1 activator-enzyme complex

por Dai, Han, Case, April W., Riera, Thomas V., Considine, Thomas, Lee, Jessica E., Hamuro, Yoshitomo, Zhao, Huizhen, Jiang, Yong, Sweitzer, Sharon M., Pietrak, Beth, Schwartz, Benjamin, Blum, Charles A., Disch, Jeremy S., Caldwell, Richard, Szczepankiewicz, Bruce, Oalmann, Christopher, Yee Ng, Pui, White, Brian H., Casaubon, Rebecca, Narayan, Radha, Koppetsch, Karsten, Bourbonais, Francis, Wu, Bo, Wang, Junfeng, Qian, Dongming, Jiang, Fan, Mao, Cheney, Wang, Minghui, Hu, Erding, Wu, Joe C., Perni, Robert B., Vlasuk, George P., Ellis, James L.
Publicado en Nat Commun (2015)