Dissecting interdomain communication within cAPK regulatory subunit type IIβ using enhanced amide hydrogen/deuterium exchange mass spectrometry (DXMS)

cAMP-dependent protein kinase (cAPK) is a heterotetramer containing a regulatory (R) subunit dimer bound to two catalytic (C) subunits and is involved in numerous cell signaling pathways. The C-subunit is activated allosterically when two cAMP molecules bind sequentially to the cAMP-binding domains,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Zawadzki, Kerri M., Hamuro, Yoshitomo, Kim, Jack S., Garrod, Siv, Stranz, David D., Taylor, Susan S., Woods, Virgil L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2003
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323995/
https://ncbi.nlm.nih.gov/pubmed/12930997
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky